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Phospho-Erk1(T202)+Erk2(T185) Monoclonal Antibody, AbBy Fluor-350 Conjugated

Applications

  • WB
  • IF
  • Flow-Cyt

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-54491r-bf350-100ul
Product Name Phospho-Erk1(T202)+Erk2(T185) Monoclonal Antibody, AbBy Fluor-350 Conjugated
Applications WB, IF, Flow-Cyt
Reactivity Human, Mouse, Rat
Specifications
Conjugation AbBy Fluor-350
Host Rabbit
Source Synthetic phospho-Peptide corresponding to residues surrounding Thr185 of human Erk2.
Modification Site Thr202+Thr185
Clonality Monoclonal
Clone # 6H2
Isotype IgG
Concentration Lot Dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 5595
Swiss Prot P27361
Subcellular location Cytoplasm, Nucleus
Background The protein encoded by this gene is a member of the MAPkinase family. MAP kinases, also known as extracellularsignal-regulated kinases (ERKs), act in a signaling cascade thatregulates various cellular processes such as proliferation,differentiation, and cell cycle progression in response to avariety of extracellular signals. This kinase is activated byupstream kinases, resulting in its translocation to the nucleuswhere it phosphorylates nuclear targets. Alternatively splicedtranscript variants encoding different protein isoforms have beendescribed. [provided by RefSeq, Jul 2008].
Application Dilution
WB 1:300-5000
IF
Flow-Cyt 1ug/Test