| Overview |
| bsm-61122r-rbitc-100ul |
| PMEL Recombinant Antibody, RBITC Conjugated |
| WB, IF |
| Human |
| Specifications |
| RBITC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human PMEL |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 6490 |
| P40967 |
| Extracellular, Secreted |
| PMEL; ME20-M; Premelanosome protein; Silver locus protein homolog; PMEL17; SILV. |
| Plays a central role in the biogenesis of melanosomes. Involved in the maturation of melanosomes from stage I to II. The transition from stage I melanosomes to stage II melanosomes involves an elongation of the vesicle, and the appearance within of distinct fibrillar structures. Release of the soluble form, ME20-S, could protect tumor cells from antibody mediated immunity. |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|