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mGluR5 Recombinant Antibody, Biotin Conjugated

Applications

  • IHC-P
  • IHC-F

Reactivity

  • Mouse
  • Rat
Overview
Catalog # bsm-61218r-biotin-100ul
Product Name mGluR5 Recombinant Antibody, Biotin Conjugated
Applications IHC-P, IHC-F
Reactivity Mouse, Rat
Specifications
Conjugation Biotin
Host Rabbit
Source KLH conjugated synthetic peptide derived from human mGluR5
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 2915
Swiss Prot P41594
Subcellular location Cell membrane
Synonyms GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5.
Background G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.
Application Dilution
IHC-P 1:200-400
IHC-F 1:100-500