| Overview |
| bsm-61337r-biotin-100ul |
| NOTCH4 Recombinant Antibody, Biotin Conjugated |
| WB |
| Human, Mouse |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Notch 4 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 4855 |
| Q99466 |
| Nucleus, Cell membrane |
| NOTC4; hNotch4; INT3; Notch homolog 4. |
| Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system. |
| Application Dilution |
| WB |
1:300-5000 |
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