| Overview |
| bsm-61416r |
| TRF1 Recombinant Antibody |
| WB, ICC/IF |
| Human |
| Mouse |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TERF1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 7013 |
| P54274 |
| Cytoplasm, Nucleus |
| TERF1; PIN2; TRBF1; TRF1. |
| Plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression. |
| Application Dilution |
| WB |
1:300-5000 |
| ICC/IF |
1:50-100 |