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DR5 Recombinant Antibody, RBITC Conjugated

Applications

  • WB
  • Flow-Cyt

Reactivity

  • Human
Overview
Catalog # bsm-61496r-rbitc-100ul
Product Name DR5 Recombinant Antibody, RBITC Conjugated
Applications WB, Flow-Cyt
Reactivity Human
Specifications
Conjugation RBITC
Host Rabbit
Source KLH conjugated synthetic peptide derived from human DR5
Clonality Recombinant
Isotype IgG
Concentration Lot dependent
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 8795
Swiss Prot O14763
Synonyms Death receptor 5; TRAIL receptor 2; TRAIL-R2; CD262; TNFRSF10B; DR5; KILLER; TRAILR2; TRICK2; ZTNFR9.
Background Receptor for the cytotoxic ligand TNFSF10/TRAIL.The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis.
Application Dilution
WB 1:300-5000
Flow-Cyt 1ug/Test