| Overview |
| bsm-61715r-pe-cy3 |
| Plexin A1 Recombinant Monoclonal Antibody, PE-Cy3 Conjugated |
| WB, FCM |
| Human, Mouse, Rat |
| Specifications |
| PE-Cy3 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Plexin A1 |
| Monoclonal |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 5361 |
| Q9UIW2 |
| Cell membrane |
| NOV; NOVP; Plexin-A1; Plexin1; PlexinA1; PLXN1; Plxna1. |
| Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. |
| Application Dilution |
| WB |
1:300-5000 |
| FCM |
1:20-100 |
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