| Overview |
| bsm-61756r-rbitc-100ul |
| PU.1/Spi1 Recombinant Antibody, RBITC Conjugated |
| WB |
| Human, Mouse |
| Specifications |
| RBITC |
| Rabbit |
| KLH conjugated synthetic peptide derived from human SPI1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 6688 |
| P17947 |
| Nucleus |
| oncogene spi1; PU.1; SFPI1; SPI 1; SPI A; Spi1. |
| Pioneer transcription factor, which controls hematopoietic cell fate by decompacting stem cell heterochromatin and allowing other transcription factors to enter otherwise inaccessible genomic sites. Once in open chromatin, can directly control gene expression by binding genetic regulatory elements and can also more broadly influence transcription by recruiting transcription factors, such as interferon regulatory factors (IRFs), to otherwise inaccessible genomic regions. |
| Application Dilution |
| WB |
1:300-5000 |
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