| Overview |
| bsm-61966r |
| TREX1 Recombinant Antibody |
| WB, IHC-P, IHC-F, IF, ICC/IF |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human TREX1 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 11277 |
| Q9NSU2 |
| AGS1; AGS5; CRV; DNase III; DRN3; HERNS; TREX1. |
| Major cellular 3'-to-5' DNA exonuclease which digests single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA) with mismatched 3' termini.Prevents cell-intrinsic initiation of autoimmunity.Acts by metabolizing DNA fragments from endogenous retroelements, including L1, LTR and SINE elements. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF |
ICC1:50-200 |
| ICC/IF |
IF |
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