| Overview |
| bsm-62258r-biotin-100ul |
| Phospho-GSK3 A/B (Tyr279/Tyr216) Recombinant Antibody, Biotin Conjugated |
| WB, IHC-P, IHC-F, IP |
| Human, Mouse, Rat |
| Specifications |
| Biotin |
| Rabbit |
| KLH conjugated synthetic peptide derived from human GSK3 alpha around the phosphorylation site of Y279 |
| Tyr279/Tyr216 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 2931 |
| P49840 |
| Cytoplasm |
| Glycogen synthase kinase-3 alpha; GSK-3 alpha; GSK3A. |
| GSK3A a proline-directed protein kinase of the GSK family. Implicated in the control of several regulatory proteins including glycogen synthase, Myb, and c-Jun. GSK3 and GSK3 have similar functions. GSK3 phophorylates tau, the principal component of neurofibrillary tangles in Alzheimer disease and is required for maximal production of amyloid plaque peptides by secretase. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IP |
1-2ug |
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