| Overview |
| bsm-62344r |
| MonoMethyl-Histone H2B type 2E (Lys117) Recombinant Antibody |
| WB, IHC-P, IHC-F, IF, ICC/IF |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human Histone H2B type 2E around the methylation site of K117 |
| Lys117 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified Polyclonal A |
| 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 8349 |
| Q16778 |
| Histone H2B |
| Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF |
ICC1:50-200 |
| ICC/IF |
IF |