| Overview |
| bsm-62442r |
| THEMIS Recombinant Antibody |
| WB, IP, Flow-Cyt, ICC/IF |
| Human, Mouse, Rat |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human THEMIS |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 387357 |
| Q8N1K5 |
| Cytoplasm, Nucleus |
| Protein THEMIS; SPOT; THEMIS; TSEPA. |
| Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals required for proper lineage commitment and maturation of T-cells. Regulates T-cell development through T-cell antigen receptor (TCR) signaling and in particular through the regulation of calcium influx and phosphorylation of Erk. |
| Application Dilution |
| WB |
1:300-5000 |
| IP |
1-2ug |
| Flow-Cyt |
1ug/Test |
| ICC/IF |
1:50-100 |
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