| Overview |
| bsm-63015r-bf350 |
| USP28 Recombinant Antibody, AbBy Fluor-350 Conjugated |
| WB, FCM, IF(IHC-P), IF(ICC) |
| Human |
| Specifications |
| AbBy Fluor-350 |
| Rabbit |
| KLH conjugated synthetic peptide derived from human USP28 |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 57646 |
| Q96RU2 |
| Nucleus |
| KIAA1515; Ubiquitin carboxyl terminal hydrolase 28; Ubiquitin thioesterase 28; UBP28. |
| Deubiquitinase involved in DNA damage response checkpoint and MYC proto-oncogene stability. Involved in DNA damage induced apoptosis by specifically deubiquitinating proteins of the DNA damage pathway such as CLSPN. Also involved in G2 DNA damage checkpoint, by deubiquitinating CLSPN, and preventing its degradation by the anaphase promoting complex/cyclosome (APC/C). |
| Application Dilution |
| WB |
1:500-2000 |
| FCM |
FCM1:50-100 |
| IF(IHC-P) |
IFIHC-P1:50-200 |
| IF(ICC) |
IFICC1:50-200 |
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