| Overview |
| bsm-63061r-cy3-100ul |
| NPHS2 Monoclonal Antibody, Cy3 Conjugated |
| WB, IF |
| Human, Mouse, Rat |
| Specifications |
| Cy3 |
| Rabbit |
| Monoclonal |
| IgG |
| Lot Dependent |
| Purified by Protein A. |
| Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
| Target |
| 7827 |
| Q9NP85 |
| nephrosis 2, idiopathic, steroid resistant; NPHS2 gene; PDCN; Podocin; SRN1; PODO_HUMAN |
| Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton. |
| Application Dilution |
| WB |
1:300-5000 |
| IF |
|
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