Thiocolchicine

Overview
Catalog #	bs-75065c-5mg
Product Name	Thiocolchicine
Specifications
Storage Buffer	Solid
Storage Condition	Stable for 2 years after receipt when stored at -20°C.
Target
Product Information	CAS Number: 2730-71-4 Molecular formula: C22H25NO5S Molecular weight: 415.5 Purity: >95% (NMR) Appearance: Yellow solid. Solubility: Soluble in ethanol or acetone. Almost insoluble in water or ether. InChiKey: CMEGANPVAXDBPL-UHFFFAOYSA-N SMILES: COC1=C(OC)C(OC)=C2C(CCC(NC(C)=O)C3=CC(=O)C(SC)=CC=C23)=C1
Description	Antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor. Axonal cytoskeleton modulator. Inhibitor of autophagosome-lysosome fusion. Apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors.