BRD-7389

Overview
Catalog #	bs-82235c-5mg
Product Name	BRD-7389
Specifications
Storage Buffer	Brown solid
Storage Condition	-20°C
Target
Product Information	Inhibits p90 ribosomal S6 kinase (RSK), IC50 = 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2 respectively1. Induces a beta-cell-like state in pancreatic apha-cells and induces insulin expression1,2. Increases the endocrine cell content and function of donor human pancreatic islets in culture1. Blocks muscarinic acetylcholine receptor-stimulated RSK activation and subsequent proliferation of SNU-407 colon cancer cells3.
Description	CAS Number: 376382-11-5 Chemical Name: 1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinolone-2,7-dione Molecular weight: 366.42 Formula: C24H18N2O2 Solubility: DMSO (35 mg/ml) Physical Properties: Brown solid Purity: 98% by TLC, NMR (Conforms)