Gue1654

Overview
Catalog #	bs-82236c-5mg
Product Name	Gue1654
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Gue1654 is a biased antagonist for the oxoeicosanoid receptor 1 (OXE-R, GPR170)1, the receptor for 5-Oxo-ETE, a proinflammatory eicosanoid2. It selectively inhibits Gβγ but not Gαi signaling upon activation of the Gαi-βγ heterotrimer by OXE-R.1,3 Gue1654 alleviated coronary artery ligation-induced ischemic myocardial injury in a mouse model.4
Description	CAS Number: 397290-30-1 Chemical Name: N-[7-(Methylthio)benzo[1,2-d:4,3-d']bisthiazol-2-yl]-α-phenylbenzeneacetamide Molecular weight: 447.59 Formula: C23H17N3OS3 Solubility: DMSO (40 mg/ml with warming) Physical Properties: Off-white solid Purity: >98% by TLC, NMR (Conforms)