LY-364947
| Overview | |
| Catalog # | bs-82281c-25mg |
| Product Name | LY-364947 |
| Specifications | |
| Storage Buffer | White or slightly yellow solid |
| Storage Condition | RT |
| Target | |
| Product Information | Selective ALK5 inhibitor, IC50 = 59, 400 and 1400 nM for TGF-β RI, TGF-β RII and MLK-7K, respectively1. Inhibits Smad2 phosphorylation induced by TGF-β as well as fibronectin expression and MDA-MB-231 cell invasion2. Abolishes resistance of glioblastoma-initiating cells to radiation3. Cell permeable. |
| Description | CAS Number: 396129-53-6 Chemical Name: 4-(3-Pyridin-2-yl-1H-pyrazol-4-yl)quinolone Molecular weight: 272.31 Formula: C17H12N4 Solubility: DMSO (25 mg/ml) Physical Properties: Beige solid Purity: 98% by TLC |
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