SRPIN340

Overview
Catalog #	bs-82286c-5mg
Product Name	SRPIN340
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Selective serine arginine protein kinase (SRPK) 1 inhibitor (Ki = 0.89 μM).1 Inhibits SRPK2 at higher concentrations. Does not significantly inhibit other SRPKs such as CLK1 and CLK4, or other classes of SR kinases. Inhibits viral replication by inhibition of host SR protein kinases.1 Modulates VEGF splicing to reduce pathological neovascularization in a rat model of retinopathy2 and controls VEGF-mediated tumor angiogenesis in xenografts3.
Description	CAS Number: 218156-96-8 Chemical Name: N-[2-(1-Piperidinyl)-5-(trifluoromethyl)phenyl]-4-pyridinecarboxamide Molecular weight: 349.35 Formula: C18H18F3N3O Solubility: DMSO (40 mg/ml) Ethanol (25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms)