STF-083010
| Overview | |
| Catalog # | bs-82292c-5mg |
| Product Name | STF-083010 |
| Specifications | |
| Storage Buffer | yellow solid |
| Storage Condition | RT |
| Target | |
| Product Information | A novel small molecule inhibitor of IRE1. It inhibits IRE1 endonuclease activity but not its kinase activity after endoplasmic reticulum stress1-3. It displays significant antimyeloma activity in model human MM xenografts1. Induces apoptosis in pancreatic cancer cells and displays growth inhibition in a clonogenic growth assay in soft agar as well as in a xenograft in vivo model of pancreatic cancer4. Active in vivo. |
| Description | CAS Number: 307543-71-1 Chemical Name: N-[(2-Hydroxy-1-naphthalenyl)methylene]-2-thiophenesulfonamide Molecular weight: 317.39 Formula: C15H11NO3S2 Solubility: DMSO (30 mg/ml) Physical Properties: yellow solid Purity: 98% by TLC, NMR (Conforms) |
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