LM11A-31

Overview
Catalog #	bs-82304c-5mg
Product Name	LM11A-31
Specifications
Storage Buffer	Pale yellow solid
Storage Condition	-20°C
Target
Product Information	A nonpeptide neurotrophic factor receptor p75 (p75NTR) agonist which promotes survival signaling in neurotrophin-responsive cells.1 Promotes functional recovery in a mouse model of spinal contusion injury.2 Protects neurogenesis after traumatic brain injury.3 Reverses cholinergic neurite dystrophy in Alzheimer’s disease mouse models.4 Stabilizes neuronal calcium, preserves mitochondrial movement and protects against HIV-associated neuropathogenesis.5 Orally active and blood-brain barrier permeant.
Description	CAS Number: 1243259-19-9 Chemical Name: (2S,3S)-2-Amino-3-methyl-N-[2-(4-morpholinyl)ethyl]pentanamide, dihydrochloride Molecular weight: 316.27 Formula: C12H25N3O2 2HCl Solubility: DMSO (20 mg/ml) Ethanol (30 mg/ml) Physical Properties: Pale yellow solid Purity: 98% by TLC NMR (Conforms)