Mithramycin A
| Overview | |
| Catalog # | bs-82383c-1mg |
| Product Name | Mithramycin A |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3. |
| Description | CAS Number: 18378-89-7 Chemical Name: Molecular weight: 1085.15 Formula: C52H76O24 Solubility: DMSO (200 mg/ml) Ethanol (10 mg/ml) Physical Properties: Yellow solid Purity: 98% by HPLC NMR (Conforms) |
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