Myriocin (ISP-1)
| Overview | |
| Catalog # | bs-82385c-5mg |
| Product Name | Myriocin (ISP-1) |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Myriocin is a fungal metabolite with potent immunosuppressant activity.1 It inhibits serine palmitoyltransferase (Ki = 0.28 nM) blocking the synthesis of ceramide.2 It was found to suppress melanoma cell proliferation by cell cycle arrest at the G 2/M phase through decreased sphingolipid levels and increased p53 and p21 (waf1/cip1) expression.3 |
| Description | CAS Number: 35891-70-4 Chemical Name: (2S,3R,4R,6E)-2-Amino-3,4-dihydroxy-2-(hydroxymethyl)-14-oxo-6-eicosenoic acid Molecular weight: 401.54 Formula: C21H39NO6 Solubility: DMSO (20 mg/ml) Physical Properties: Off-white solid Purity: >98% |
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