Doramapimod
| Overview | |
| Catalog # | bs-82403c-5mg |
| Product Name | Doramapimod |
| Specifications | |
| Storage Buffer | White or off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Potently and selectively inhibits p38 MAPK by simultaneously binding to the ATP-binding domain and an allosteric site.1 (IC50=18 nM). Displays anti-inflammatory activity2 but differential effects on inflammatory genes3. Cell permeable. |
| Description | CAS Number: 285983-48-4 Chemical Name: 1-[5-tert-Butyl-2-(4-methylphenyl)pyrazol-3-yl]-3-[4-(2-morpholin-4-ylethoxy)naphthalene-1-yl]urea Molecular weight: 527.66 Formula: C31H37N5O3 Solubility: DMSO (50 mg/ml) Ethanol (30 mg/ml) Physical Properties: White or off-white solid Purity: 98% by TLC, NMR (Conforms) |
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