H89 · 2HCl
| Overview | |
| Catalog # | bs-82411c-5mg |
| Product Name | H89 · 2HCl |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | H-89 is a commonly used inhibitor of protein kinase A (PKA IC50 = 140 nM). Inhibits a variety of other kinases including S6K1 (IC50 = 80 nM), MSK1 (120 nM), ROCK II (270 nM), PKBα (2.6 µM), PKD, PRK2, RSK1 and 2, SGK, AMPK, CHK1 and MAPKAP-K1b (2.8 µM).1,2 |
| Description | CAS Number: 127243-85-0 Chemical Name: N-[2-[[3-(4-Bromophenyl)-2-propen-1-yl]amino]ethyl]-5-isoquinolinesulfonamide dihydrochloride Molecular weight: 519.28 Formula: C20H20BrN3O2S·2HCl Solubility: DMSO (50 mg/ml) Water (10 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms) |