Gabexate mesylate
| Overview | |
| Catalog # | bs-82435c-10mg |
| Product Name | Gabexate mesylate |
| Specifications | |
| Storage Buffer | Off-white solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | A serine protease inhibitor inhibiting plasmin, kallikrein, thrombin as well as trypsin, which attenuates pancreatic fibrosis.1 Reduces weight gain and improves metabol-ism in obese rodent models.2 In clinical use (in Japan) for pancreatitis.3 Inhibits influenza virus replication in human tracheal epithelial cells.4 Reduces infection of Calu-3 lung cells by SARS-CoV-2 (responsible for COVID-19) via inhibition of the serine protease TMPRSS2 required for viral spike protein priming.5 |
| Description | CAS Number: 56974-61-9 Chemical Name: 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]benzoic acid, ethyl ester, methanesulfonate Molecular weight: 417.48 Formula: C16H23N3O4 ∙ CH3SO3H Solubility: DMSO (50 mg/ml) Water (50 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC NMR (Conforms) |