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Tryptanthrin

Overview
Catalog # bs-82439c-5mg
Product Name Tryptanthrin
Specifications
Storage Buffer Yellow solid
Storage Condition -20°C
Target
Product Information A indoloquinazoline alkaloid found in various plant species and possessing intriguing pharmacological activities.1 Suppresses activation of BV2 microglia cells following LPS treatment and reduces production of proinflammatory cytokines via Nrf2, HO-1 and NFκB signaling.2 Displays antiinflammatory activity targeting IL-17.3 Inhibits indoleamine 2,3-dioxygenase 2 (IDO2) with an IC50 of 5-17 μM.4 Induces growth inhibition and neuronal differentiation in human neuroblastoma LA-N-1 cells.5
Description CAS Number: 13220-57-0

Chemical Name: Indolo(2,1-b)quinazoline-6,12-dione

Molecular weight: 248.24

Formula: C15H8N2O2

Solubility: DMSO (30 mg/ml)

Physical Properties: Yellow solid

Purity: 98% by HPLC, NMR (Conforms)