Reserpine

Overview
Catalog #	bs-82559c-1g
Product Name	Reserpine
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	Indole alkaloid isolated from Rauwolfia serpentina which acts as a potent antihypertensive agent. Irreversibly inhibits both isoforms of vesicular monoamine transporter VMAT1 and 2, Ki=34 and 12 nM, respectively.1,2 May be used to pharmacologically deplete monoamines in various animal models.3 Inhibits the multidrug resistance protein P-glycoprotein, IC50=0.5 mM.3 Reserpine-induced hypokinesia is considered a useful animal model of Parkinson’s disease.5
Description	CAS Number: 50-55-5 Chemical Name: (3β,16β,17α,18β,20α)-11,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-yohimban-16-carboxylic acid, methyl ester Molecular weight: 608.68 Formula: C33H40N2O9 Solubility: DMSO (35 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms)