Z-DEVD-FMK
| Overview | |
| Catalog # | bs-82608c-1mg |
| Product Name | Z-DEVD-FMK |
| Specifications | |
| Storage Buffer | Lyophilized solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Z-DEVD-FMK (210344-95-9) is a cell-permeable trimethyl ester form of the irreversible caspase-3 inhibitor DEVD-FMK (fluoromethylketone) with IC50 = 130 nM.1,2 Methyl esters confer cell permeability and are hydrolyzed to the active COOH form via intracellular esterases. Inhibits caspase-3-dependent apoptosis and pyroptosis in a variety of cell lines.3,4 Active in vivo.5 |
| Description | CAS Number: 210344-95-9 Chemical Name: Benzyloxycarbonyl-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-fluoromethylketone Molecular weight: 668.67 Formula: C30H41FN4O12 Solubility: DMSO (20 mg/ml) Physical Properties: Lyophilized solid Purity: >98% by TLC, NMR (Conforms) |
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