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RSL3

Overview
Catalog # bs-82677c-5mg
Product Name RSL3
Specifications
Storage Buffer Off-white solid
Storage Condition -20°C
Target
Product Information RSL3 inhibits glutathione peroxidase (GPX4) inducing ferroptosis.1,2 Effectively induces ferroptosis in glioblastoma cells.3 Everolimus in combination with RSL3 synergistically inhibits the viability of renal cell carcinoma (RCC) cells suggesting a mechanism by which RCC drug resistance may be overcome.4
Description CAS Number: 1219810-16-8

Chemical Name: (1S,3R)-Methyl 2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylate

Molecular weight: 440.88

Formula: C23H21ClN2O5

Solubility: DMSO (45 mg/ml)

Physical Properties: Off-white solid

Purity: >98% by HPLC, NMR (Conforms)