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DJ-V 159

Overview
Catalog # bs-82694c-5mg
Product Name DJ-V 159
Specifications
Storage Buffer Off-white solid
Storage Condition RT
Target
Product Information GPRC6A is the receptor for osteocalcin as well as structurally unrelated ligands including L-amino acids, cations and anabolic steroids.1 GPRC6A is a potential therapeutic target for treating type 2 diabetes.2 DJ-V 159 is an agonist at GPRC6A which activates ERK and upregulates cAMP levels in HEK-193 cells expressing GPRC6A It stimulates insulin secretion in mouse -cells and lowers blood glucose in mouse models.3
Description CAS Number: 2253744-53-3

Chemical Name: N1,N3-Bis(4-cyano-3-(trifluoromethyl)phenyl)isophthalamide

Molecular weight: 502.37

Formula: C24H12F6N4O2

Solubility: DMSO (60 mg/ml)

Physical Properties: Off-white solid

Purity: 98% by TLC NMR (Conforms)