BD1063 dihydrochloride

Overview
Catalog #	bs-82826c-5mg
Product Name	BD1063 dihydrochloride
Specifications
Storage Buffer	Off-white solid
Storage Condition	-20°C
Target
Product Information	BD1063 is potent and selective sigma-1 antagonist (IC50’s: sigma1 = 9nM, sigma2 = 449nM).1 BD1063 abolished mechanical and thermal hyperalgesia in mice with carrageenan-induced acute inflammation by enhancing the action of endogenous opioid peptides of immune origin in a sigma1 dependent manner.2 BD1063 potentiated µ-opioid antinociception in mice in a sigma-dependent manner.3 BD-1063 has been used in animal models to successfully treat compulsive eating4 and excessive ethanol drinking5.
Description	CAS Number: 206996-13-6 Chemical Name: 1-[2-(3,4-Dichlorophenyl)ethyl]-4-methylpiperazine dihydrochloride Molecular weight: 346.13 Formula: C13H18Cl2N2·2HCl Solubility: Water (>25 mg/ml) Physical Properties: Off-white solid Purity: 98% by HPLC NMR (Conforms)