Tiagabine hydrochloiride

Overview
Catalog #	bs-82852c-10mg
Product Name	Tiagabine hydrochloiride
Specifications
Storage Buffer	Off white or beige solid
Storage Condition	-20°C
Target
Product Information	Tiagabine is a clinically useful anticonvulsant.1 It is also used to treat anxiety/panic disorder2 and neuropathic pain3. Tiagabine inhibits GABA-reuptake (IC50 [3H]GABA uptake = 67 nM) via inhibiting GABA transporter 1(GAT1) blocking both neuronal and glial GABA re-uptake.4,5
Description	CAS Number: 145821-59-6 Chemical Name: (3R)-1-[4,4-Bis(3-methylthiophen-2-yl)but-3-enyl]piperidine-3-carboxylic acid hydrochloride Molecular weight: 412.00 Formula: C20H25NO2S2·HCl Solubility: DMSO (>25 mg/ml) Ethanol (>25 mg/ml) Water (>30 mg/ml) Physical Properties: Off white or beige solid Purity: >98% by HPLC NMR (Conforms)