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TH257

Overview
Catalog # bs-82861c-5mg
Product Name TH257
Specifications
Storage Buffer White to off-white glassy solid
Storage Condition -20°C
Target
Product Information TH257 is a potent (IC50’s = 238 nM (LIMK1) and 91 nM (LIMK2)) and highly selective (no off-targets against 468 kinases) allosteric inhibitor of LIM kinase 1/2.1 It inhibited neurite outgrowth in N1E-115 cells in a dose-dependent manner.
Description CAS Number: 2244678-29-1

Chemical Name: N-Butyl-4-[(phenylamino)sulfonyl]-N-(phenylmethyl)benzamide

Molecular weight: 422.54

Formula: C24H26N2O3S

Solubility: DMSO (25 mg/ml)

Physical Properties: White to off-white glassy solid

Purity: >98% by HPLC NMR (Conforms)