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Afatinib

Overview
Catalog # bs-82885c-10mg
Product Name Afatinib
Specifications
Storage Buffer Pale yellow solid
Storage Condition -20°C
Target
Product Information Afatinib is a clinically useful kinase inhibitor approved for the treatment of non-small cell lung cancer. It is a potent and highly selective inhibitor of mutant and wild-type EGFR (IC50 = 0.5 nM) and HER2 (IC50 = 14 nM).
Description CAS Number: 850140-72-6

Chemical Name: N-[4-[(3-Chloro-4-fluorophenyl)amino]-7-[[(3S)-tetrahydro-3-furanyl]oxy]-6-quinazolinyl]-4(dimethylamino)-2E-butenamide

Molecular weight: 485.94

Formula: C24H25ClFN5O3

Solubility: DMSO (>25 mg/ml) Ethanol (25 mg/ml)

Physical Properties: Pale yellow solid

Purity: 99% by HPLC, NMR (Conforms)