TTFA

Overview
Catalog #	bs-82924c-100mg
Product Name	TTFA
Specifications
Storage Buffer	Pale yellow solid
Storage Condition	-20°C
Target
Product Information	TTFA blocks the respiratory chain complex II causing inhibition of mitochondrial respiration. Respiratory chain complex II inhibition is caused via binding of TTFA to two ubiquinone binding sites, Qp and Qd.1 Inhibition of Complex II by TFA has been shown to cause a delay in overall cell cycle progression leading to oxidative stress.2,3 TTFA also was found to inhibit porcine liver carboxylesterase (IC50 = 0.54 µM).4
Description	CAS Number: 326-91-0 Chemical Name: Thenoyltrifluoroacetone; 4,4,4-Trifluoro-1-(2-thienyl)-1,3-butanedione Molecular weight: 222.18 Formula: C8H5F3O2S Solubility: DMSO (25 mg/ml) Ethanol (25 mg/ml) Physical Properties: Pale yellow solid Purity: >98%, NMR (Conforms)