Glumetinib
| Overview | |
| Catalog # | bs-82990c-5mg |
| Product Name | Glumetinib |
| Specifications | |
| Storage Buffer | Beige solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Highly selective (2400-fold selectivity against a panel of 312 kinases) and potent (IC50 = 0.42 nM) inhibitor of c-Met kinase. It induced tumor regression in MET-driven CDX (MKN-45, SNU-5, EBC-1) and PDX (4 NSCLC, 5 HCC) tumor models. |
| Description | CAS Number: 1642581-63-2 Chemical Name: 6-(1-Methylpyrazol-4-yl)-1-[6-(1-methylpyrazol-4-yl)imidazo[1,2-a]pyridine-3-yl]sulfonylpyrazolo[4,3-b]pyridine Molecular weight: 459.48 Formula: C21H17N9O2S Solubility: DMSO (>25 mg/ml) Physical Properties: Beige solid Purity: 98% by HPLC NMR (Conforms) |
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