Darunavir

Overview
Catalog #	bs-83063c-10mg
Product Name	Darunavir
Specifications
Storage Buffer	White solid
Storage Condition	-20°C
Target
Product Information	Darunavir is a very potent (IC50 = 3 nM against lab HIV-1 strains and clinical isolates) HIV-1 protease inhibitor that is in clinical use.1,2 Also potent against multi-PI-resistant HIV-1 strains from patient samples. Darunavir has been investigated as a potential anti-SARS-CoV2 therapeutic with mixed results.3-6
Description	CAS Number: 206361-99-1 Chemical Name: [(3aS,4R,6aR)-2,3,3a,5,6a-Hexahydrofuro[2,3-b]furan-4-yl] N-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl]carbamate Molecular weight: 547.67 Formula: C27H37N3O7S Solubility: DMSO (>25 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMR (conforms)