Deferasirox

Overview
Catalog #	bs-83066c-10mg
Product Name	Deferasirox
Specifications
Storage Buffer	Off-white to white solid
Storage Condition	-20°C
Target
Product Information	Clinically useful iron chelator used in long term care of ß-thalassemia and other heavily transfused hematological patients.1,2 It has been shown to potent inhibitor of JumonjiC Domain-Containing Histone Demethylases (IC50’s = KDM4A(JMJD2A) 4.76 µM, KDM5A(JARID1A) 5.00 µM, KDM6B(JMJD3) 3.95 µM).3 Deferasirox has also been investigated as a potential anticancer agent.4-6
Description	CAS Number: 201530-41-8 Chemical Name: 4-[3,5-bis(2-Hydroxyphenyl)-1,2,4-triazol-1-yl]benzoic acid Molecular weight: 373.36 Formula: C21H15N3O4 Solubility: DMSO (10 mg/ml) Physical Properties: Off-white to white solid Purity: >98% by HPLC NMR (Conforms)