BAM15

Overview
Catalog #	bs-83090c-5mg
Product Name	BAM15
Specifications
Storage Buffer	Pale-yellow solid
Storage Condition	-20°C
Target
Product Information	A mitochondrial protonophore uncoupler with fewer off-target effects (EC50 = 270 nM in L6 myoblast mitochondria.)1,2 Compared to FCCP, an uncoupler of equal potency, BAM15 stimulates a higher maximum rate of mitochondrial respiration and does not depolarize the plasma membrane.2 Stimulates energy expenditure, protects against obesity and improves glycemic control in rodent models.3 Reverses diet-induced obesity and insulin resistance in mice.4 Attenuates transportation-induced apoptosis in iPS-differentiated retinal tissue.5
Description	CAS Number: 210302-17-3 Chemical Name: N5,N6-bis(2-Fluorophenyl)-[1,2,5]oxadiazolo[3,4-b]pyrazine-5,6-diamine Molecular weight: 340.29 Formula: C16H10F2N6O Solubility: DMSO (35 mg/ml) Physical Properties: Pale-yellow solid Purity: 98% by TLC NMR (Conforms)