Phenylhexyl isothiocyanate

Overview
Catalog #	bs-83106c-5mg
Product Name	Phenylhexyl isothiocyanate
Specifications
Storage Buffer	Colorless to pale yellow liquid
Storage Condition	-20°C
Target
Product Information	Isothiocyanate constituents of cruciferous vegetables are potent chemopreventive agents for carcinogen-induced cancers in rodents.1 PHITC was the most potent in a series of synthetic arylalkyl isothiocyanates at inhibition of tumorigenicity by NNK, a tobacco-derived nitrosamine, in a mouse model.2 It was also found to induce apoptosis and inhibit leukemia cell growth in vivo3 and was shown to have dual function as a histone deacetylase inhibitor and hypomethylating agent4. PHITC was also shown to restore the activity of mutant p53 and reactivate the p53 pathway in human myeloid leukemia M2 cells.5
Description	CAS Number: 133920-06-6 Chemical Name: 6-Isothiocyanatohexylbenzene Molecular weight: 219.35 Formula: C13H17NS Solubility: DMSO (25 mg/ml) Physical Properties: Colorless to pale yellow liquid Purity: >98% by TLC NMR (Conforms)