DUSP9 Polyclonal Antibody

$Lane 1: Human HepG2 cell lysates; Lane 2: Human Huh7 cell lysates; Lane 3: Human HeLa cell lysates; Lane 4: Human A431 cell lysates probed with DUSP9 Polyclonal Antibody, Unconjugated (bs-14461R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.$

Lane 1: Human HepG2 cell lysates; Lane 2: Human Huh7 cell lysates; Lane 3: Human HeLa cell lysates; Lane 4: Human A431 cell lysates probed with DUSP9 Polyclonal Antibody, Unconjugated (bs-14461R) at 1:1000 dilution and 4\u00b0C overnight incubation. Followed by conjugated secondary antibody incubation at room temperature for 60 min.

Applications

Reactivity

Human
Mouse
Rat

Overview
Catalog #	bs-14461r-100ul
Product Name	DUSP9 Polyclonal Antibody
Applications	WB
Reactivity	Human, Mouse, Rat
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human DUSP9
Immunogen Range	300-350/384
Clonality	Polyclonal
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Store at -20°C for 12 months.
Target
Gene ID	1852
Swiss Prot	Q99956
Synonyms	Dual specificity phosphatase 9; Dual specificity protein phosphatase 9; DUS9_HUMAN; DUSP9; MAP kinase phosphatase 4; Mitogen activated protein kinase phosphatase 4; Mitogen-activated protein kinase phosphatase 4; MKP 4; MKP-4; MKP4; serine/threonine specific protein phosphatase.
Background	The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus. [provided by RefSeq, Jul 2008]
Application Dilution
WB	1:300-5000