| Overview |
| bs-16176r-100ul |
| FOXR2 Polyclonal Antibody |
| IHC-P, IHC-F, IF(ICC), IF |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human FOXR2 |
| 51-150/311 |
| Polyclonal |
| IgG |
| 1ug/ul |
| Purified by Protein A. |
| 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Store at -20°C for 12 months. |
| Target |
| 139628 |
| Q6PJQ5 |
| Forkhead box protein N6; Forkhead box protein R2; FOXN6; FOXR2_HUMAN. |
| The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be associated with the pathogenesis of various cancers. FOXR2 (Forkhead box protein R2), also known as FOXN6 (Forkhead box protein N6), is a 311 amino acid nuclear protein that belongs to the FOX family and contains one fork-head DNA-binding domain. Like other members of the FOX family, FOXR2 is not abundantly expressed in normal tissues but is found at very high levels in breast cancer and primary cancer cell lines and is thought to act as a transcription factor. Through chromosomal aberrations such as retroviral integration, gene amplification or translocation, FOXR2 may be involved the development of certain invasive carcinomas. |
| Application Dilution |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IF(ICC) |
1:50-200 |
| IF |
|
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