Phospho-TNK1 (Tyr277) Polyclonal Antibody

Overview
Catalog #	bs-3450R
Product Name	Phospho-TNK1 (Tyr277) Polyclonal Antibody
Applications	WB, ELISA, IHC-P, IHC-F, IF(IHC-P), IF(IHC-F), IF(ICC)
Specificity	This phosphorylation site is homologous across the listed species.
Reactivity	Mouse
Predicted Reactivity	Human, Rat, Dog, Pig, Horse, Rabbit, GuineaPig
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic phosphopeptide derived from human TNK1 around the phosphorylation site of Tyr277 [GR(p-Y)VM]
Modification Site	Tyr277
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4_. Store at -20_ for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	8711
Swiss Prot	Q13470
Subcellular location	Cytoplasm, Cell membrane
Synonyms	Non-receptor tyrosine-protein kinase TNK1; CD38 negative kinase 1; TNK1
Background	Involved in negative regulation of cell growth. Has tumor suppressor properties. Plays a negative regulatory role in the Ras-MAPK pathway. May function in signaling pathways utilized broadly during fetal development and more selectively in adult tissues and in cells of the lymphohematopoietic system. Could specifically be involved in phospholipid signal transduction.
Application Dilution
WB	1:300-5000
ELISA	1:500-1000
IHC-P	1:200-400
IHC-F	1:100-500
IF(IHC-P)	1:50-200
IF(IHC-F)	1:50-200
IF(ICC)	1:50-200