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CRKL Polyclonal Antibody

Lane 1: Hela cell lysates; Lane 2: CRKL knockout (KO) HeLa cell lysates probed with CRKL Polyclonal Antibody, Unconjugated (bs-55046R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: Hela cell lysates; Lane 2: CRKL knockout (KO) HeLa cell lysates probed with CRKL Polyclonal Antibody, Unconjugated (bs-55046R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: LO2 cell lysates; Lane 2: Jurkat cell lysates; Lane 3: SKOV3 cell lysates; Lane 4: Mouse Brain lysates; Lane 5: Rat heart cell lysates probed with CRKL Polyclonal Antibody, Unconjugated (bs-55046R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.
Lane 1: LO2 cell lysates; Lane 2: Jurkat cell lysates; Lane 3: SKOV3 cell lysates; Lane 4: Mouse Brain lysates; Lane 5: Rat heart cell lysates probed with CRKL Polyclonal Antibody, Unconjugated (bs-55046R) at 1:1000 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:20000 for 60 min at 37˚C.

Applications

  • WB
  • IF

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bs-55046R
Product Name CRKL Polyclonal Antibody
Applications WB, IF
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Recombinant fusion protein containing a sequence corresponding to amino acids 1-303 of human CRKL (NP_005198.1).
Clonality Polyclonal
Clone # #REF!
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20C for 12 months.
Target
Gene ID 1399
Swiss Prot P46109
Subcellular location Cytoplasm, Nucleus
Synonyms Crk L; Crk like protein; Crkol; HGNC:2363; Oncogene CrkL; V crk avian sarcoma virus CT10 oncogene homolog like; V crk sarcoma virus CT10 oncogene homolog avian like; CRKL_HUMAN.
Background This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
Application Dilution
WB 1:300-5000
IF

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