RNF21 Polyclonal Antibody

Lane 1: Mouse Lung lysates; Lane 2: Mouse Placenta lysates probed with RNF21 Polyclonal Antibody, Unconjugated (bs-9244R) at 1:300 dilution and 4˚C overnight incubation. Followed by conjugated secondary antibody incubation at 1:10000 for 60 min at 37˚C.

Applications

WB
IHC-P
IF(IHC-P)

Reactivity

Mouse

Predicted Reactivity

Human
Rat
Pig

Overview
Catalog #	bs-9244R
Product Name	RNF21 Polyclonal Antibody
Applications	WB, IHC-P, IF(IHC-P)
Reactivity	Mouse
Predicted Reactivity	Human, Rat, Pig
Specifications
Conjugation	Unconjugated
Host	Rabbit
Source	KLH conjugated synthetic peptide derived from human RNF21
Clonality	Polyclonal
Clone #	#REF!
Isotype	IgG
Concentration	1ug/ul
Purification	Purified by Protein A.
Storage Buffer	0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition	Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Target
Gene ID	53840
Synonyms	P1; Interferon Responsive Finger Protein 1; Ring Finger Protein 21; Ring finger protein 21 interferon responsive; RNF21; TRIM 34; TRIM34; Tripartite mot containing protein 34; TRI34_HUMAN.
Background	Tripartite motif-containing protein 34 (TRIM34), also known as RING finger protein 21 (RNF21) or interferon-responsive finger protein 1 (IFP1), is a 488 amino acid member of the TRIM family, also known as the RING-B-box coiled-coil (RBCC) family. Members of the RBCC family have an N-terminal RING finger, followed by one or two zinc-binding domains (B-box domains), a leucine coiled-coil region and a variable C-terminal domain. Three isoforms of TRIM34 exist as a result of alternative splicing events. Isoform 1, the most abundant isoform, is highly expressed in placenta, spleen, colon and peripheral blood leukocytes. Studies have shown that Interferon (IFN) stimulation leads to an upregulation of TRIM34. These findings suggest that TRIM34 maybe a downstream effector that mediates IFN activities.
Application Dilution
WB	1:300-5000
IHC-P	1:200-400
IF(IHC-P)	1:50-200