| Overview |
| bsm-62264r |
| RYK Recombinant Antibody |
| WB, IHC-P, IHC-F, IP, IF, Flow-Cyt, ICC/IF |
| Human |
| Specifications |
| Unconjugated |
| Rabbit |
| KLH conjugated synthetic peptide derived from human RYK |
| Recombinant |
| IgG |
| Lot dependent |
| Purified by Protein A. |
| 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol |
| Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles. |
| Target |
| 6259 |
| P34925 |
| Nucleus |
| ERK 3; JTK5; JTK5A; Ryk; RYK1; Vik. |
| May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development. |
| Application Dilution |
| WB |
1:300-5000 |
| IHC-P |
1:200-400 |
| IHC-F |
1:100-500 |
| IP |
1-2ug |
| IF |
|
| Flow-Cyt |
1ug/Test |
| ICC/IF |
1:50-100 |
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