Alkaline Phosphatase, Tissue Non-Specific isozyme Polyclonal Antibody, Biotin Conjugated
Applications
| Overview | |
| Catalog # | bs-1535R-Biotin |
| Product Name | Alkaline Phosphatase, Tissue Non-Specific isozyme Polyclonal Antibody, Biotin Conjugated |
| Applications |
WB
ELISA
IHC-P
IHC-F
|
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from AP-TNAP/ALPL |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 11647 |
| Swiss Prot | P09242 |
| Subcellular location | Cytoplasm, Nucleus, Cell membrane |
| Synonyms | Akp2; TNAP; Akp-2; APTNAP; TNSALP; Alkaline phosphatase, tissue-nonspecific isozyme; AP-TNAP; Alkaline phosphatase 2; Alkaline phosphatase liver/bone/kidney isozyme; Alpl |
| Background | Alkaline phosphatase (ALP) removes phosphate groups from the 5' end of DNA and RNA, and from proteins, at high pH. Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease. |
| Application Dilution | |
| WB | 1:300-5000 |
| ELISA | 1:500-1000 |
| IHC-P | 1:200-400 |
| IHC-F | 1:100-500 |