LINGO2 Polyclonal Antibody
Applications
Reactivity
| Overview | |
| Catalog # | bs-18284r |
| Product Name | LINGO2 Polyclonal Antibody |
| Applications |
WB
|
| Reactivity | Human, Mouse, Rat |
| Specifications | |
| Conjugation | Unconjugated |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human LINGO2 |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 158038 |
| Swiss Prot | Q7L985 |
| Synonyms | LERN3; Leucine rich repeat and Ig domain containing 2; Leucine rich repeat neuronal 6C; Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2; Leucine-rich repeat neuronal protein 3; Leucine-rich repeat neuronal protein 6C; LIGO2_HUMAN; LINGO2; LRRN6C. |
| Background | Lingo-2 (leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 2), also known as LERN3 (leucine-rich repeat neuronal protein 3) or LRRN6C, is a 606 amino acid single-pass type I membrane protein. Lingo-2 contains 1 immunoglobulin-like C2-type domain and 13 leucine-rich repeats. Lingo-2 is a member of the LRR gene family and has been linked to essential tremor and Parkinsons disease. Lingo-2 has a high degree of homology (61%) with Lingo-1, a regulator of neuronal death, and the expression of Lingo-2 seems to be restricted to neuronal tissue. |
| Application Dilution | |
| WB | 1:300-5000 |