IL-23R Polyclonal Antibody, Biotin Conjugated
Applications
Reactivity
Predicted Reactivity
| Overview | |
| Catalog # | bs-22608R-Biotin |
| Product Name | IL-23R Polyclonal Antibody, Biotin Conjugated |
| Applications |
WB
|
| Reactivity | Human |
| Predicted Reactivity | Rat |
| Specifications | |
| Conjugation | Biotin |
| Host | Rabbit |
| Source | KLH conjugated synthetic peptide derived from human IL-23R |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1ug/ul |
| Purification | Purified by Protein A. |
| Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Storage Condition | Store at -20C for 12 months. |
| Target | |
| Gene ID | 149233 |
| Swiss Prot | Q5VWK5 |
| Subcellular location | Cell membrane |
| Synonyms | IL23 Receptor; IL-23R; IL23R; interleukin 23 receptor; IL 23R; IL-23 receptor; IL23R_HUMAN; Interleukin-23 receptor. |
| Background | Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis. Subunit : Heterodimer with IL12RB1. In presence of IL23, the heterodimer forms the IL23 receptor. Interacts with JAK2 and in presence of IL23 with STAT3. |
| Application Dilution | |
| WB | 1:300-5000 |